中国卒中杂志2017，Vol.12Issue(3)：219-222,4.DOI:10.3969/j.issn.1673-5765.2017.03.005
2012-2014年北京缺血性卒中患者阿司匹林和氯吡格雷联合使用率分析
The Usage Rate of Clopidogrel in Combination with Aspirin in Ischemic Stroke Patients in 2012-2014
摘要
Abstract
Objective To analyze the usage rate of clopidogrel in combination with aspirin through big data analysis. Methods Using the Beijing Medical Insurance Database for Employers, patients with the primary diagnosis of ischemic stroke or transient ischemic attack (TIA) and related syndrome from January 1, 2012 to December 31, 2014 were identified as the study subjects and were divided into two subsets according to International Classification of Diseases-10 (ICD), with June, 2013 as the cutoff point. The two subsets both covered 18-month long period. Descriptive analysis was applied to compare the difference in the usage rate of clopidogrel in combination with aspirin between the two subsets. Subgroup analysis was also conducted in ischemic stroke patients and TIA patients separatively. Results A total of 6296188 cases and 101587 subjects were included during study period. During July, 2013 to December, 2014, 876.9 (±129.8) cases used clopidogrel in combination with aspirin each month, accounting for 14.7% of the total cases. And the number was 649.9 (±129.8) from January, 2012 to June, 2013, accounting for 12.3% of the total cases. The usage rates were 14.5% and 9.1% in patients with primary diagnosis as ischemic stroke and TIA each month before June, 2013, respectively. The usage rates became higher after June, 2013 (20.2% and 11.1% for ischemic stroke and TIA, respectively). Before June, 2013, 18.3% of the participants used clopidogrel in combination with aspirin. Afterwards, the proportion rate increased up to 22.2%. Conclusion Among the patients with ischemic stroke and TIA of Beijing Medical Insurance Database, the usage rate of clopidogrel in combination with aspirin after June, 2013 was higher than that of before June, 2013.关键词
缺血性卒中/抗血小板治疗/大数据Key words
Ischemic stroke/Anti-platelet therapy/Big data引用本文复制引用
杨成,魏晨璐,田耀华,唐迅,胡永华..2012-2014年北京缺血性卒中患者阿司匹林和氯吡格雷联合使用率分析[J].中国卒中杂志,2017,12(3):219-222,4.基金项目
国家自然科学基金(81230066,81573226) （81230066,81573226）
