浙江医学2017，Vol.39Issue(1)：49-51,3.
脑转移瘤同期推量适形放疗与调强放疗的剂量学研究
Dosimetric study of 3DCRT and IMRT for whole-brain radiotherapy with simultaneous integrated boost to brain metastases
摘要
Abstract
Objective To investigate the dosimetric differences of 3DCRT and IMRT for whole-brain radiotherapy with simultaneous integrated boost to brain metastases.Methods Forty one previously treated cancer patients with brain metastases were replanned using 3DCRT and IMRT,respectively.The prescription dose was 3000cGy/10 fractions for whole brain (PTV),and 4000cGy/10 fractions for individual brain metastases (PGTV) simultaneously.The conformation number (CN) and homogeneity index (HI) of the target,and the monitor units (MU) were compared.Results Both treatment plans met the clinical requirements.The target dose conformity of IMRT was better than that of 3DCRT (P＜0.05).The homogeneity index and monitor units of 3DCRT were better than those of IMRT (P＜0.05).For the cases with 2 metastases which were not on the same slice,and 3 or 4 metastases which were on the same slice,there was no statistical difference in the target dose conformity between 3DCRT and IMRT(P ＞0.05),while the homogeneity index and monitor units of 3DCRT was better than IMRT(P＜0.05).For the cases with 3 metastases which were not on the same slice,there was no statistical difference in the target dose conformity and homogeneity index between 3DCRT and IMRT (P ＞0.05),while the monitor units of 3DCRT was better than that of IMRT (P＜0.05).Conclusion Two types of plans can satisfy the clinical requirements.Under some special conditions,such as 2 or 3 metastases which were not on the same slice,or 3 or 4 metastases which were on the same slice,the 3DCRT plan is better.关键词
同期推量/适形放疗/调强放疗/剂量学Key words
Simultaneous integrated boost/3DCRT/IMRT/Dosimetry引用本文复制引用
倪玲琴,应申鹏,刘艳梅,王勇,吴朝霞,David Huang..脑转移瘤同期推量适形放疗与调强放疗的剂量学研究[J].浙江医学,2017,39(1):49-51,3.基金项目
台州市科技计划项目(1402ky10) （1402ky10）
