浙江医学2017，Vol.39Issue(2)：118-119,132,3.
透明质酸钠凝胶预防妇产科手术后盆腹腔粘连的临床效果观察
Application of sodium hyaluronate gel during gynecologic and obstetric surgery prevents postoperative pelvic or abdominal adhesion
摘要
Abstract
Objective To observe the effect of sodium hyaluronate gel (HA) on postoperative pelvic or abdominal adhesion in gynecologic and obstetric surgery.Methods Clinical data of 7 000 patients undergoing gynecologic and obstetric surgery were retrospectively analyzed.HA was applied and fully coated on the lesions and corresponding peritoneum before resection and on the surface of the wound after resection in 3 652 cases (HA group),while HA was not applied during operation in 3 348 cases (control group).The occurrence of postoperative pelvic or abdominal adhesion were observed and compared between two groups.Results The overall incidence rates of pelvic or abdominal adhesion in HA group were lower than those in control group (P＜0.05) 1 week,3 months and 6 months after surgery.The incidence rates of pelvic or abdominal adhesion in patients with initial operation were lower than those in patients with reoperation,the incidence rates in patients with minimally invasive surgery were lower than patients with open surgery (all P＜0.05) both in HA group or control group.Conclusion HA as a barrier preparation applied during gynecologic and obstetric surgery can effectively prevent postoperative pelvic or abdominal adhesions.关键词
透明质酸钠凝胶/妇产科手术/盆腹腔粘连Key words
Sodium hyaluronate gel/Gynecological surgery/Pelvic or abdominal adhesion引用本文复制引用
潘一红,程娅,林伟平,林慧敏,谢吉蓉,金芙蓉,陶俊贞,史春娟,李瑾..透明质酸钠凝胶预防妇产科手术后盆腹腔粘连的临床效果观察[J].浙江医学,2017,39(2):118-119,132,3.基金项目
吴阶平医学基金会临床科研专项资助基金课题(2011-LK10008) （2011-LK10008）
