浙江医学2017，Vol.39Issue(4)：284-287,4.DOI:10.12056/j.issn.1006-2785.2017.39.4.2016-1241
病理T1期孤立性非小细胞肺癌淋巴结转移特征及其影响因素
Clinicopathological features and risk factors for lymphatic metastasis in pathological T1 primary isolated non-small cell lung cancer
摘要
Abstract
Objective To investigate the clinicopathological features and risk factors for lymphatic metastasis of pathological T1 primary isolated non-small cell lung cancer (NSCLC).Methods The clonicopathological features of lymphatic metastasis in 681 cases of pT1 NSCLC were retrospectively analyzed.Logistic model was used to analyze the risk factors for lymphatic metastasis.Results The lymphatic metastasis rate of pT1 NSCLC was 10.1％ (69/681),while the rated of skip metastasis to mediastinal lymph node was 2.3％(16/681).Lymphatic metastasis rate in male patients,with central type,in lower right lung and lower left lung,T1a and squamous cell carcinomas was higher than that in female patients,with peripheral type,in upright left and right lung,T1b and T1c,and adenocarcinoma(all P＜0.05).Multivariate Logistic regression model showed that the central type,pT1c,pleural invasion,intravenous invasion were the risk factors for lymphatic metastasis (all P＜0.05).Female NSCLC patients with a tumor located in the upper left lung had higher skip lymphatic metastasis rate (all P＜0.05).Conclusion The tumor size,tumor position,tumor type,pleural and venous invasion are independent risk factors for lymphatic metastasis in NSCLC patients.Peripheral NSCLC patients with a tumor of 1.0 cm or less in diameter,and no pleural invasion should be recommend for lymph node sampling or selective lymph node dissection.关键词
非小细胞肺癌/肿瘤大小/淋巴结转移/危险因素Key words
Non-small cell lung cancer/Tumor size/Lymphatic metastasis/Risk factors引用本文复制引用
陈志军,竺王玉,柴振达,王善军,王兆宇,张永奎..病理T1期孤立性非小细胞肺癌淋巴结转移特征及其影响因素[J].浙江医学,2017,39(4):284-287,4.基金项目
浙江省科技计划项目(2015C33254) （2015C33254）
