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自噬与骨肉瘤的研究进展

吴宏增 王进 冯和林

肿瘤防治研究2017,Vol.44Issue(2):153-156,4.
肿瘤防治研究2017,Vol.44Issue(2):153-156,4.DOI:10.3971/j.issn.1000-8578.2017.02.015

自噬与骨肉瘤的研究进展

Advances of Autophagy in Osteosarcoma

吴宏增 1王进 1冯和林1

作者信息

  • 1. 050011 石家庄,河北医科大学第四医院骨科
  • 折叠

摘要

Abstract

Autophagy has become a hot issue in the field of cancer research as a mechanism of cell defense and stress regulation.Autophagy abnormal is related to energy metabolism,cell death,inflammatory response and drug resistance in malignant tumor.New breakthrough has not been achieved in the overall survival of osteosarcoma (OS) in the past 20 years.Surgery combined with chemotherapy is still the most effective treatment for OS.Currently,several studies confirmed that autophagy is significantly related to the chemotherapy of OS.Therefore,we review the advances of autophagy in OS.

关键词

自噬/骨肉瘤/化疗

Key words

Autophagy/Osteosarcoma/Chemotherapy

分类

医药卫生

引用本文复制引用

吴宏增,王进,冯和林..自噬与骨肉瘤的研究进展[J].肿瘤防治研究,2017,44(2):153-156,4.

基金项目

河北省自然基金面上项目(H2015206314) (H2015206314)

河北省医学科学研究重点课题计划(20160159) (20160159)

肿瘤防治研究

OACSCDCSTPCD

1000-8578

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