肿瘤防治研究2017,Vol.44Issue(2):153-156,4.DOI:10.3971/j.issn.1000-8578.2017.02.015
自噬与骨肉瘤的研究进展
Advances of Autophagy in Osteosarcoma
摘要
Abstract
Autophagy has become a hot issue in the field of cancer research as a mechanism of cell defense and stress regulation.Autophagy abnormal is related to energy metabolism,cell death,inflammatory response and drug resistance in malignant tumor.New breakthrough has not been achieved in the overall survival of osteosarcoma (OS) in the past 20 years.Surgery combined with chemotherapy is still the most effective treatment for OS.Currently,several studies confirmed that autophagy is significantly related to the chemotherapy of OS.Therefore,we review the advances of autophagy in OS.关键词
自噬/骨肉瘤/化疗Key words
Autophagy/Osteosarcoma/Chemotherapy分类
医药卫生引用本文复制引用
吴宏增,王进,冯和林..自噬与骨肉瘤的研究进展[J].肿瘤防治研究,2017,44(2):153-156,4.基金项目
河北省自然基金面上项目(H2015206314) (H2015206314)
河北省医学科学研究重点课题计划(20160159) (20160159)