中国现代中药2017，Vol.19Issue(1)：44-50,63,8.DOI:10.13313/j.issn.1673-4890.2017.1.009
中药材规范化种植茯苓化学成分研究
Chemical Constituents from Sclerotium of Poria cocos Cultivated in GAP Base for Chinese Medicinal Materials
摘要
Abstract
Objective:To study the chemical constituents of 95％ ethanol aqueous extract of the sclerotium of Poria cocos(Schw.)Wolf..Methods:The compounds were separated and purified by repeated column chromtography on silica gel and high performance liquid chromatography,and their structures were determined by spectroscopic data analyses.Results:Fourteen comounds were obtained and identified as ergosta-7,22-dien-3β-ol (1),3-epidehydrotumlosic acid (2),3-O-acetyl-16α-hydroxytrametenolic acid (3),polyporenic acid C (4),dehydropachymic acid (5),pachymic acid (6),6α-hydroxypolyporenic acid C (7),dehydrotumlosic acid (8),tumlosic acid (9),29-hydroxypolyporenic acid C (10),poriacosone A (11),3β,16α-dihydroxylanosta-7,9 (11),24-trien-21-oic acid (12),25-hydroxypachymc acid (13),poriacosone B (14),respectively.Conclusion:The sclerotium of P.cocos cultivated in Good Agricultural Practices (GAP)Base for Chinese Medicinal Materials contains abundant and characteristic lanostane-type triterpenoids,which are principal bioactive substance foundation of the sclerotium of P.cocos.关键词
中药材规范种植/茯苓/多孔菌科/羊毛脂烷型三萜/生物活性物质基础Key words
Poria cocos cultivated in GAP Base for Chinese Medicinal Materials/Poria cocos/Polyporaceae/lanostane-type triterpenoids/bioactive substance foundation引用本文复制引用
郑艳,杨秀伟..中药材规范化种植茯苓化学成分研究[J].中国现代中药,2017,19(1):44-50,63,8.基金项目
“十二五”国家科技支撑专项(2011BAI07B08) （2011BAI07B08）
