中国现代中药2017，Vol.19Issue(1)：148-153,6.DOI:10.13313/j.issn.1673-4890.2017.1.029
中药有效成分作用于肝星状细胞抗肝纤维化分子机制研究进展
Advances in Mechanistic Studies on Anti-liver Fibrosis of Active Components of Chinese Medicine by Targeting Hepatic Stellate Cells
摘要
Abstract
Hepatic fibrosis is an integral clinicopathological condition of chronic liver disease.Inhibition of HSC activation and clearance of activated HSC become key to the prevention and treatment of hepatic fibrosis.Chinese medicine antiliver fibrosis of active by measures of multi-channel,multi-target and a variety of cytokines and cell pathway in hepatic stellate cells,molecular mechanim of the activation and apoptosis of HSC and the studies on the anti-liver fibrosis of active ingredients were reviewed in this paper,which could provide some references for the further study about the anti-hepatic fibrosis.关键词
中药有效成分/肝星状细胞/肝纤维化/分子机制Key words
Active components of Chinese medicine/hepatic stellate cells (HSCs)/hepatic fibrosis/mechanism引用本文复制引用
常虹,郭凯,孟洪宇,刘树民..中药有效成分作用于肝星状细胞抗肝纤维化分子机制研究进展[J].中国现代中药,2017,19(1):148-153,6.基金项目
国家重点基础研究项目(973计划)(2013CB531804) （973计划）
