北京生物医学工程2017，Vol.36Issue(1)：82-86,5.DOI:10.3969/j.issn.1002-3208.2017.01.13
基于Fisher判别分析的多囊卵巢综合征中医证候分布规律
Distribution regularity of TCM syndromes in patients with polycystic ovary syndrome based on Fisher discriminant analysis
摘要
Abstract
Objective Polycystic ovary syndrome (PCOS) is a chronic ovulation disorders and is characterized by hyperandrogenism and continuous anovulation.The objective is to discuss the application of Fishier discriminant analysis (FDA) on Chinese medicine syndrome type distribution in patients with PCOS and the relationship with sexual hormones between the symptoms.Methods Chinese medicine syndrome types of 62 PCOS patients were differentiated,including 21 cases with kidney deficiency syndrome,22 cases with kidney deficiency and phlegm stagnation syndrome and 19 cases with kidney liver depression syndrome.These cases covered single symptoms,accompanied symptoms and are separated with the method of twice grouping.The cases with kidney deficiency syndrome were separated with Logistic regression first,and then the remaining accompanied symptoms were for the second classification with Fishier discriminant analysis method.The correlation on sex hormones between the symptoms was analyzed with statistical method.Results Fishier discriminant analysis was used for the separation of accompanied symptoms and the correct rate was 87.8％.The luteinizing hormone (LH) level was significantly higher in the groups of kidney deficiency and phlegm stagnation syndrome than in the group of kidney liver depression syndrome(P＜0.05)and the prolactin (PRL) level was significantly higher in the group of kidney liver depression syndrome than in the group of kidney deficiency and phlegm stagnation syndrome (P＜0.05).Conclusions The test results of Fisher discriminant function model are in good agreement with those obtained from the actual situation,and may be used as an auxiliary tool for the exploration on Chinese medicine syndrome type distribution in patients with PCOS.There is a correlation between syndrome type and sexual hormone levels.关键词
中医证候/辨证分型/多囊卵巢综合征/二次分型/Fisher判别分析/回归分析/性激素Key words
TCM syndromes/syndrome differentiation/polycystic ovary syndrome/double classification/Fisher discriminant analysis/regression analysis/sex hormone分类
医药卫生引用本文复制引用
章浩伟,孙洋洋,刘颖,王子楠..基于Fisher判别分析的多囊卵巢综合征中医证候分布规律[J].北京生物医学工程,2017,36(1):82-86,5.基金项目
上海市科委医学领先项目(12401907700)资助 （12401907700）
