川北医学院学报2017，Vol.32Issue(1)：16-19,4.DOI:10.3969/j.issn.1005-3697.2017.01.005
蛛网膜下腔小剂量布比卡因用于剖宫产手术的理想注药时长探讨
Discussion of the ideal subarachnoid low-dose bupivacaine injection time length in spinal anesthesia for cesarean section
摘要
Abstract
Objective:To discuss the ideal time length of subarachnoid 0.5％ bupivacaine 7.5 mg for cesarean section through L2-L3 interval puncture.Methods:150 pregnancy women,aged 18 ～ 45 year,of ASA Ⅰ-Ⅱ,undergoing cesarean section,according to the subarachnoid injection time length,were randomly divided into three groups,group A (20 ～ 25 s),group B (26 ～ 35 s),group C (36 ～45 s).In L2-L3 interval puncture,0.5％ bupivacaine 1.5 mL was injected into subarachnoid space,epidural cavity as a remedial measures for spinal anesthesia.The mean arterial pressure (MAP),anesthesia level,adverse reactions (nausea,vomiting),the reaction to skin incision,intraoperative traction reaction,vasopressor usage,and neonatal Apgar score were recorded.Results:After being injected bupivacaine 5 min,10 min,15 min,MAP of group A was lower than the other two groups(P ＜ 0.05),between group B and group C,there were no differences (P ＞ 0.05).The anesthesia level of group A at 5 min,10 m in and 15 min were higher than the other two groups(P ＜ 0.05).At 10min and 15 min,the anesthesia levels of group B were higher than group C (P ＜ 0.05).The incidence of nausea and vomiting in group A was significantly higher than that in group B and group C (P ＜ 0.05).The rate of ephedrine used in group A (16％) was significantly higher than that of B and C groups (2％,2％) (P ＜ 0.05).In group C,the pain reaction was no difference between group A and group B when skin incision (P ＞ 0.05),during the operation,the patients with abdominal rectus sheath and peritoneal traction were more than group A and group B (P ＜ 0.05).There was no difference among the three groups in neonatal Apgar score (P ＞ 0.05).Conclusions:To intrathecal 0.5％ bupivacaine 1.5 mL for cesarean delivery,the ideal subarachnoid injection time length was 26 ～ 35s.关键词
腰麻/布比卡因/剖宫产术Key words
Spinal anesthesia/Bupivacaine/Cesarean section分类
医药卫生引用本文复制引用
陈旭,樊雅玲,卓刚..蛛网膜下腔小剂量布比卡因用于剖宫产手术的理想注药时长探讨[J].川北医学院学报,2017,32(1):16-19,4.基金项目
四川省医学科研青年创新课题(Q15060) （Q15060）
