动物营养学报2016，Vol.28Issue(6)：1633-1640,8.DOI:10.3969/j.issn.1006-267x.2016.06.001
肠道内分泌与营养素感应系统
Enteroendocrine and Nutrient Sensing System
摘要
Abstract
A variety of nutrients and chemicals in the gastrointestinal (GI) tract exert physiologic effects via enteroendocrine and nutrient sensing system.As a part of enteroendocrine and nutrient sensing system,enteroendocrine cells can detect luminal nutrients via nutrient sensing receptors (amino acids sensing receptors,fatty acids sensing receptors,glucose sensing receptors,etc.).Enteroendocrine cells not only can regulate nutrient absorption and metabolism,but also can secret kinds of gut-brain peptides (glucagon-like peptide-1,peptide YY and cholecystokinin,etc.).Gut-brain peptides through the gut-brain axis,which is composed of central neuron system,automatic nervous system and enteric nervous system,regulate host feeding behaviors and other physiologic functions.This review summarized recent advances on animal enteroendocrine system,gut-brain axis and nutrient sensing receptors.关键词
肠道营养感应/肠道内分泌系统/脑肠轴/营养素感应受体Key words
nutrient sensing/enteroendocrine system/gut-brain axis/sensing receptor分类
农业科技引用本文复制引用
高侃,慕春龙,余凯凡,朱伟云..肠道内分泌与营养素感应系统[J].动物营养学报,2016,28(6):1633-1640,8.基金项目
国家重点基础研究发展计划项目(973项目)(2013CB127300) （973项目）
江苏省自然科学基金(BK20130058) （BK20130058）
教育部博士点基金项目(20130097130005) （20130097130005）
