摘要
Abstract
Objective:To investigate etiology and clinical analysis in children with alanine aminotrasferase (ALT) rising.Methods:The data of hospitalized children with ALT abnormalities were statistical analyzed retrospectively.Results:The number of males was significantly more than females.In these children of ALT abnormalities,849 cases were infants under one year old,245 cases were between 1 year to 2 years old,229 cases were between 3 to 5 years old,260 cases were between 6 to 12 years old,44 cases were between 13 to 16 years old.A total of 709 cases were attributed to infection,which was the main cause of ALT abnormality.Five hundreds and sixty six cases were virus infected,Ctomegalovirus (CMV),Epstein Barr virus (EBV) and Respiratory syncytial virus (RSV) infection were the most common etiology.Then,in non-infective diseases,ALT abnormality was more commonly resulted by connective tissue diseases,trauma,and liver or biliary duct structure abnormalities.However,the etiologies of 447 cases were still unknown.In this study,126 cases showed jaundice,472 cases showed hepatomegaly,204 cases showed splenomegaly,180 cases showed lymphadenovarix,and 51 cases showed bleeding tendency.Conclusion:Infants were the main groups of ALT abnormality.Infection,especially virus infection was the most common etiology.In non-infective diseases,connective tissue disease was more common.In addition,surgical disease,drug substance,hereditary metabolic disease,and so on,can lead to abnormal ALT.关键词
儿童/丙氨酸氨基转移酶/病因Key words
children/alanine aminotransferase/etiology分类
医药卫生
