分析化学2017，Vol.45Issue(2)：253-260,8.DOI:10.11895/j.issn.0253-3820.160761
聚丙烯腈和二氧化硅复合纤维膜富集-高分辨质谱法测定烟气中的有害化合物
Determination of Hazard Compounds in Cigarette Smoke by High-Resolution Orbitrap Mass Spectrometry Combined with Nanofiber Membrane Extraction
摘要
Abstract
A new method was proposed for analysis of the organic compounds in cigarette smoke by high resolution Orbitrap mass spectrometry based on polyacrylonitrile-silica (PAN-SiO2) nanofiber membrane extraction and methanol elution.Hydrophobic PAN-SiO2 nanofiber membrane which was used to enrich small molecular organic compounds in cigarette smoke was prepared by the technology of electrospinning.Several parameters including the concentrations of PAN and SiO2 nanopartical,elecrospining voltage,needle aperture and flow rate of spinning solution were optimized.Under the optimal conditions,a PAN-SiO2 nanofiber membrane with good adsorption performance and great physical strength was obtained.A total of 21 compounds including acetone,styrene,acrolein,isoprene,and acrylonitrile were identified by analyzing the cigarette smoke with Orbitrap MS spectrometry in the positive ion mode.Six organic acids including salicylic acid,malic acid and lactic acid were detected in negative ion mode.The limits of detection and quantification for nicotine were 0.071 ng/L and 0.236 ng/L,respectively.关键词
聚丙烯腈和二氧化硅复合纤维膜/高分辨质谱技术/香烟烟气/有害化合物Key words
Polyacrylonitrile-silica nanofiber membranes/High resolution mass spectrometry/Cigarette smoke/Hazard organic compounds引用本文复制引用
申素素,梁大鹏,陈焕文,苏蕊..聚丙烯腈和二氧化硅复合纤维膜富集-高分辨质谱法测定烟气中的有害化合物[J].分析化学,2017,45(2):253-260,8.基金项目
本文系吉林省科技厅重点科技攻关项目(No.20160204027YY),吉林省教育厅“十三五”科学技术研究项目(No.2016002)资助 （No.20160204027YY）
