口腔疾病防治2017，Vol.25Issue(4)：227-230,4.DOI:10.12016/j.issn.2096-1456.2017.04.005
类风湿关节炎和慢性牙周炎临床指标的相关性研究
Relationship of clinical index between rheumatoid arthritis and chronic periodontitis
摘要
Abstract
Objective To explore the relationship betweenrheumatoid arthritis (RA) and chronic periodontitis (CP). Methods A total of 48 RA patients were recruited from the Rhematology Department of The First Affiliated Hospital of Shantou University Medical College (SUMC). RA patients were matched on age and gender with healthy controls, who were recruited from the Stomatology Department. Dental parameters including unstimulated salivary flow rate(UWS), stimulated salivary flow rate (SWS), bleeding on probe (BOP), periodontal probing pocket (PD), clinical attachment level (CAL) and decayed, missing and filling (DMF) were recorded in all cases. Erythrocyte sedimentation rate (ESR), C-reac-tive protein (CRP) and Anticyclic citrullinated peptide antibody (Anti-CCP) were also recorded in RA patients. Results There were significant difference between RA group and health control group on salivary flow rate, BOP, PD, CAL and DMF (P<0.001). Higher percentage of RA patients were diagnosed as periodontal disease than those in con-trol group (P<0.001). There was relationship between CAL and Anti-CCP antibody (P<0.001). Conclusion RA pa-tients have higher risk of CP, and there might be relationship between RA and CP.关键词
慢性牙周炎/类风湿关节炎/抗环瓜氨酸肽抗体/唾液流速/临床附着水平Key words
Chronic periodontitis/Rheumatoid arthritis/Anticycliccitrullinated peptide antibody/Salivary flow rate/Clinical attachment level分类
医药卫生引用本文复制引用
辛蔚妮,侯志铎,龚瑶..类风湿关节炎和慢性牙周炎临床指标的相关性研究[J].口腔疾病防治,2017,25(4):227-230,4.基金项目
广东省医学科学技术研究基金(A2014442) （A2014442）
