国际病理科学与临床杂志2017，Vol.37Issue(1)：35-40,6.DOI:10.3978/j.issn.2095-6959.2017.01.007
陶氏健骨汤治疗原发性骨质疏松症的临床效果
Clinical efficacy of Taoshi jiangu decoction in the treatment of primary osteoporosis
摘要
Abstract
Objective:To observe the dinical efficacy of Taoshi jiangu decoction on osteoporosis.Methods:One hundred and twenty patients with osteoporosis were randomly divided into treatment and control groups.Patients were treated by Taoshi jiangu decoction in a treatment group and Caltrate D in a control group.The E2,T,HYP,bone glaprotein (BGP),alkaline phosphatase (ALP),U-Ca,TRAP,parathyroid hormone (PTH),CT,S-Ca and S-P were tested.Results:The TCM clinical symptoms were relieved in the two groups.And there was statistical difference on pain of the back,soreness and weakness of the lumbar region and difficulty ofwalking.After the treatment,PTH and S-Ca reduced and the calcitonin (CT) increased in two groups,with statistical difference (P＜0.05).The E2 and T increased in treatment group (P＜0.05),while the change in control group showed no statistical difference (P＞0.05);ALP and BGP increased in two groups,with statistical difference (P＜0.05);and ALP and BGP showed higher in the treatment group than those in the control group,with statistical difference (P＜0.05).The U-HYP/Cr,U-Ca/Cr and TRAP reduced in two groups (P＜0.05),and U-HYP/Cr,U-Ca/Cr and TRAP showed lower in the treatment group than those in the control group,with statistical difference (P＜0.05).Conclusion:Taoshi jiangu decoction can increase estrogen levels,inhibit bone resorption and promote bone formation in patients with osteoporosis.It is effective for osteoporosis.关键词
陶氏健骨汤/骨质疏松症/临床研究Key words
Taoshi jiangu decoction/osteoporosis/clinical study引用本文复制引用
郁啸云,刘淑玮,盛韶山..陶氏健骨汤治疗原发性骨质疏松症的临床效果[J].国际病理科学与临床杂志,2017,37(1):35-40,6.基金项目
温岭市科技局科研项目(2013C31BC0002). This work was supported by Wenling Municipal Science and Technology Bureau (2013C31BC0002),P.R.China. （2013C31BC0002）
