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TRPM7与乳腺癌的研究进展

王欣玮

临床与病理杂志2017,Vol.37Issue(3):608-613,6.
临床与病理杂志2017,Vol.37Issue(3):608-613,6.DOI:10.3978/j.issn.2095-6959.2017.03.028

TRPM7与乳腺癌的研究进展

Recent progress of TRPM7 and breast cancer

王欣玮1

作者信息

  • 1. 中国药科大学基础医学与临床药学学院,南京 210009
  • 折叠

摘要

Abstract

Transient receptor potential (TRP) superfamily are non-selective cation channels. As a member of TRPM subfamily, TRPM7 has received much attention for its unique serine/threonine kinase domain, ubiquitous distribution and various physiological functions. Numerous studies have demonstrated that abnormal expression and function of TRPM7 channels are closely related to the formation and growth of breast cancer. So far, metastatic breast cancer cannot be cured and is the leading cause of mortality among patients with breast cancer.

关键词

瞬时电位受体通道/TRPM7/乳腺癌/转移/侵袭

Key words

transient receptor potential channels/TRPM7/breast cancer/metastasis/invasion

引用本文复制引用

王欣玮..TRPM7与乳腺癌的研究进展[J].临床与病理杂志,2017,37(3):608-613,6.

基金项目

江苏省卫生厅科研项目(H201327).This work was supported by Research Projects of Public Health Department of Jiangsu Province, P. R. China (H201327). (H201327)

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