广西科学2017，Vol.24Issue(1)：7-14,8.DOI:10.13656/j.cnki.gxkx.20170116.004
糖苷合成酶及应用的研究进展
Current Progress in Glycosynthase and Its Application
摘要
Abstract
Glycosylation can not only improve the physiochemical properties of biological macromolecules and small-molecule compounds,such as water solubility and stability, but also enhance their original bioactivity or confer a new activity.At present,extraction,chemical synthesis and enzymatic synthesis are the main tools of obtaining glycosylated products.However,the first two methods often show poor product diversity,low yield or poor specificity.The enzymatic glycosylation based on glycosyltransferase and glycosynthase can be a good solution to these obstacles and exhibits a number of advantages.As glycosyltransferase has been reviewed previously,this paper summarizes the recent progress of glycosynthase and provides reference for the development and application of multifunctional glycosynthase.关键词
糖苷合成酶/糖基化修饰/生物大分子/黄酮/抗生素Key words
glycosynthase/glycosylation/macromolecules/flavonoids/antibiotics分类
生物科学引用本文复制引用
孟岚,吴旭日,陈依军..糖苷合成酶及应用的研究进展[J].广西科学,2017,24(1):7-14,8.基金项目
国家自然科学基金项目(81502961)和高等学校博士学科点专项科研基金项目(20130096120006)资助. （81502961）
