广州医药2017，Vol.48Issue(2)：40-42,3.DOI:10.3969/j.issn.1000-8535.2017.02.011
醒脑静联合连续肾脏替代疗法对脓毒症相关性脑病的疗效评价
Evaluation of curative effect of Xingnaojing combined with continuous renal replacement therapy on sepsis associated encephalopathy
摘要
Abstract
Objective To investigate the curative effect of Xingnaojing combined with continuous renal replacement therapy on sepsis associated encephalopathy. Methods 76 cases of sepsis associated encephalopathy in our hospital from June 2014 to June 2016 were selected as the research objects, and they were divided into two groups according to the random number table method, 38 cases in each group. The observation group were treated with Xingnaojing combined with continuous renal replacement therapy. The control group was given continuous renal replacement therapy. The clinical efficacy of two groups were compared before and after treatment about the Glasgow coma (Glasgow coma scale, GCS) score, neuron specific enolase (neuron-specifie enolase, NSE) content, C-reactive protein (C-reactive protein, CRP)content, and the length of the consciousness recovery time and pyretolysis time. Results In the observation group, the total effective rate was 89.47%. Compared with the control group. it increased significantly (P<0.05);After treatment the GCS score in the observation group was significantly higher than the control group, the content of NSE and CRP were significantly lower than the control group, the differences were statistically significant (P<0.01);In the observation group, after treatment the pyretolysis time, consciousness recovery time was significantly lower than the control group(P<0.01). Conclusion The curative effect of Xingnaojing combined with continuous renal replacement therapy on sepsis associated encephalopathy is significant and may effectively shorten the pyretolysis and the recovery of consciousness time, which is worthy of clinical application.关键词
醒脑静/连续肾脏替代疗法/脓毒症/疗效Key words
Xingnaojing injection/Continuous renal replacement therapy/Sepsis/Curative effect引用本文复制引用
吴冠祺,黄永光,霍保善..醒脑静联合连续肾脏替代疗法对脓毒症相关性脑病的疗效评价[J].广州医药,2017,48(2):40-42,3.基金项目
佛山市科学技术局医学科研项目(2015AB00369) （2015AB00369）
