基础医学与临床2017，Vol.37Issue(4)：463-467,5.
术前诊断为子宫内膜不典型增生的子宫内膜癌患者的处理
Management of endometrioid carcinomapatients with preoperative diagnosis of endometrial hyperplasia
单莹 1金滢 1李艳 1王永学 1曾靖 1韩甜甜 1宋晓 1潘凌亚1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院 妇产科,北京 100730
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and treatments of endometrioid carcinoma patients with preoperative diagnosis of endometrial hyperplasia.Methods From 2005 to 2010, 404 patients were diagnosed with endometrioid carcinoma after hysterectomy.Among these patients,44 of them were diagnosed atypical endometrial hyperplasia(AEH) preoperatively.Retrospectively analysis the characteristics of these patients with SPSS13.0.Results Among the 44 cases, all of them were grade G1 disease, and 39 of them received comprehensive staging surgery.14(32%)young cases preserved bilateral ovaries.9 cases(20%) were given adjuvant radiology.No recurrence was detected during the median follow up of 52 months.Compared to the premenstrual group, although no statistical difference was detected, more patients with risk factors of deep myometrium invasion(4/22 vs 1/22) and lymph-vascular space invasion(LVSI, 3/22 vs 0/22) in the postmenstrual group.Compared to the patients who diagnosed with endometrioid cancer(EC) preoperatively, there are more patients with grade G1(P=0.000), fewer patients received adjuvant chemotherapy(P=0.003) and fewer recurrence(P=0.019) in AEH group.Conclusions The endomtrioid cancer patients who diagnosed with atypical hyperplasia preoperatively have better prognosis.Hysterectomy with bilateral ovaries preserved is acceptable in young patients.Post menopause patients have more risk factors of deep myometrium invasion and LVSI.关键词
子宫内膜不典型增生/子宫内膜样癌Key words
endometrial hyperplasia/endometrial carcinoma分类
医药卫生引用本文复制引用
单莹,金滢,李艳,王永学,曾靖,韩甜甜,宋晓,潘凌亚..术前诊断为子宫内膜不典型增生的子宫内膜癌患者的处理[J].基础医学与临床,2017,37(4):463-467,5.
