基础医学与临床2017，Vol.37Issue(4)：561-566,6.
外排体在非小细胞肺癌中的研究进展
Progress in researches on exosomes in non-small cell lung cancer
摘要
Abstract
Exosomes are vesicle-like structures generated and secreted actively by all kinds of cells.They contain proteins, nucleic acids and also lipids from the original cells, functioning in interactions between cells by shuttling cellular cargoes, and regulation of immune response in the microenvironment.Besides, they play important roles in the oncogenesis and progression of lung neoplasms.Considerable studies have demonstrated great potentials of exosomal proteins and microRNAs as biomarkers for diagnosis, prognosis prediction and treatment of lung cancers, including immunotherapy and targeted delivering of anti-tumor drugs based on exosomes.关键词
外排体/肺癌/临床试验/生物标志物/液体活检Key words
exosome/non-small cell lung cancer/clinical trials/biomarker/liquid biopsy分类
医药卫生引用本文复制引用
李凯迪,李文哲,朱凌,杨延莲,梁乃新,李单青..外排体在非小细胞肺癌中的研究进展[J].基础医学与临床,2017,37(4):561-566,6.基金项目
协和中青年科研基金(PUMCH-2016-2.25) （PUMCH-2016-2.25）
北京协和医学院青年教师培养基金(14-2014zlgc0717) （14-2014zlgc0717）
北京协和医院教学改革项目(2014zlgc0135) （2014zlgc0135）
