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青年肺癌分子遗传学以及预后的研究进展

宋勇 潘贤慧

解放军医学杂志2017,Vol.42Issue(3):181-185,5.
解放军医学杂志2017,Vol.42Issue(3):181-185,5.DOI:10.11855/j.issn.0577-7402.2017.03.01

青年肺癌分子遗传学以及预后的研究进展

Molecular genetics and prognosis of lung cancer in young patients: Research highlights

宋勇 1潘贤慧1

作者信息

  • 1. 210002 南京 南京军区南京总医院(南京大学医学院附属金陵医院)呼吸和危重症医学科
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摘要

Abstract

Differed from the elderly patients with lung cancer,the younger patients with lung cancer,less than 50 years old,present unique clinical features.Recently,the incidence of lung cancer in young people has shown a rising trend,making the research on this field more valuable.At present,molecular targeted therapy is one of the most popular areas of non-small-cell lung cancer (NSCLC),and researches are focused on the epidermal growth factor receptor (EGFR) and echinoderm microtubule associated protein like4-anaplastic lymphoma kinase (EML4-ALK).In addition,the previous researches revealed the differences between the young and elderly patients with lung cancer on molecular genetics and prognosis,so the researches on prognostic factors for young patients with lung cancer are of great clinical significance.The present paper will focus on the aspects of pathogenesis,molecular genetics and prognosis in young patients with lung cancer.

关键词

非小细胞肺癌/青年/年龄/分子遗传学/EML4-ALK融合,表皮生长因子受体/治疗/预后

Key words

non-small cell lung cancer/young/age/molecular genetics/echinoderm microtubule associated protein like4-anaplastic lymphoma kinase/epidermal growth factor receptor/treatment/prognosis

分类

医药卫生

引用本文复制引用

宋勇,潘贤慧..青年肺癌分子遗传学以及预后的研究进展[J].解放军医学杂志,2017,42(3):181-185,5.

解放军医学杂志

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