吉林中医药2017，Vol.37Issue(2)：170-173,4.DOI:10.13463/j.cnki.jlzyy.2017.02.018
慢传输型便秘与血瘀的实验研究
Experimental study on slow transit constipation and "blood stasis"
摘要
Abstract
Objective To discuss the relationship between slow transit constipation and traditional Chinese medicine "blood stasis".Methods Build module in rats with rhubarb granules by gastric slow transit constipation model is set up.The control group was treated with distilled water of same volume.By laser doppler blood flow meter probes inserted into the living rats anus,compared two groups of rats of intestinal mucosal blood flow perfusion and blood flow velocity;Measurement of rats serum NO by nitrate reductase,method of enzyme linked immunosorbent assay (ELISA) to detect the level of serum endothelin in rats,observed two groups content of serum nitric oxide (NO) and endothelin levels.To discuss the relationship between slow transit constipation and traditional Chinese medicine "blood stasis".Results The intestinal mucosal blood perfusion and blood flow velocity of the model group were significantly different from those of the control group (P＜0.05),and the model group was significantly higher than the control group;The first black stool time of the model group was significantly different from the control group (P＜0.05),and the model group was significantly longer than the control group,Serum NO and Endothelin (ET1) were significant different from experimental group (P＜0.05).Conclusion Slow transit constipation model was successfully established,there is relationship between transmission constipation and "blood stasis".关键词
慢传输型便秘/血瘀/实验研究Key words
slow transit constipation/blood stasis/experimental study分类
医药卫生引用本文复制引用
姚秋园,于永铎,付原琰..慢传输型便秘与血瘀的实验研究[J].吉林中医药,2017,37(2):170-173,4.基金项目
辽宁省科技厅科技计划项目(编号:2012225018)辽宁省教育厅科学研究一般项目(编号:L2015348) （编号:2012225018）
