机械科学与技术2017,Vol.36Issue(2):202-206,5.DOI:10.13433/j.cnki.1003-8728.2017.0207
感应电场作用下神经元模型的放电机制及稳定性分析
Discharge Mechanism and Stability Analysis of Neuron Model Exposed to Induced Electric Field
摘要
Abstract
This paper presents the equilibrium and stability of Morris-Lecar(ML) neuron model exposed to induced electric field.Based on the variation of the field-induced membrane depolarization,the equilibrium and bifurcation behaviors of three basic classes of neurons are investigated.The discharge mechanism of neurons simulated by electromagnetic fields is revealed by introducing transformed phase portraits with the equilibrium curve.Results show that bifurcations can lead to the movement of neuronal membrane potential V around the equilibrium curve,and different types of firing patterns,including bursting,synchronous spiking and sub-threshold oscillations.Meanwhile,neurons exhibit different kinds of periodic firing patterns in the simulation of periodic sinusoidal induced electric field.The study can provide theoretical reference for the extremely low frequency electromagnetic field in treating neurological diseases,and has potential application value for the brain cognitive.关键词
感应电场/ML神经元模型/放电机制/分岔/平衡曲线Key words
induced electric fields/Morris-Lecar neuron model/firing mechanism/bifurcation/equilibrium curve分类
生物科学引用本文复制引用
都琳,曹子露,张莹..感应电场作用下神经元模型的放电机制及稳定性分析[J].机械科学与技术,2017,36(2):202-206,5.基金项目
国家自然科学基金项目(11672233,11302169,11672232)与中央高校基本科研业务费专项资金项目资助 (11672233,11302169,11672232)