摘要
Abstract
Objective To investigate the drug-resistance of common pathogenic bacteria from a hospital in 2014 and to provide evidences for rational use of antibiotics in the clinic.Methods 1 221 strains of bacteria were isolated from clinical specimens in 2014.The pathogens were identified and retrospectively analyzed statistically by Zhuhai D1 Medical Biotech L-96 automated microbial identification system.Results Among all the 1 221 isolates,36.04％ (n=440) were Gram-positive bacteria;63.96％ (n=781) were Gram-negative bacteria.The three major Gram-positive bacteria were Staphylococcus aureus (12.20％,n=149),Coagulase-negative Staphylococcus sp.(10.07％,n=123),and Enterococcus sp.(10.16％,n=124);The top two Gram-negative bacteria were Escherichia coli (20.06％,n=245),and Klebsiella pneumoiae (13.27％).The most common non-fermentative bacteria included Pseudomonas aeruginosa (11.71％,n=143) and Acinetobacter baumanii (9.99％,n=122).In Staphylococcus,MRSA and MRCNS detection rates were 76.71％ of S.aureus and 81.4％ of Coagulase-negative Staphylococcus,respectively.No vancomycin and Teicoplanin resistant Staphylococcus had been found.In Gram-negative bacteria,detection rates of ESBLs were 77.2％ of E.coli and 26.0％ of K.pneumoiae,both were equally sensitive to carbapenems.Conclusion Hospital's bacterial drug resistance is increased,among them the Gram-negative bacteria dominate.The constant surveillance and control of bacterial antibiotics resistance are crucial to the rational application of antibiotics and prevention of nosocomial infection.关键词
细菌耐药性/抗菌药物/革兰阴性杆菌/革兰阳性球菌Key words
Bacterial resistance/Antibiotic drugs/Gram-negative bacilus/Gram-positive coccidia分类
医药卫生
