临床与实验病理学杂志2016，Vol.32Issue(12)：1371-1373,1378,4.DOI:10.13315/j.cnki.cjcep.2016.12.013
CT引导下经皮肺穿刺细胞学和组织学联合检查的诊断价值
Diagnostic value of cytopathological diagnosis in combination with histopathological diagnosis for lung biopsy specimens under CT guidance
赵媛 1赵永刚 1陈昊 1张智弘2
作者信息
- 1. 南京医科大学临床医学院连云港市第一人民医院病理科,连云港222002
- 2. 南京医科大学第一附属医院病理科,南京210029
- 折叠
摘要
Abstract
Purpose To investigate the value of cytopathological diagnosis in combination with histopathological diagnosis for peripherial and diffuse lung diseases by biopsy specimens under CT guidance.Methods A total of 370 cases of lung biopsy specimens under CT guidance were reviewed.The correlation between cytopathological diagnosis and histopathological diagnosis was analyzed.The sensitivity and false negative rate of cytopathological diagnosis,histopathological diagnosis and the combinational diagnosis method were calculated,and the accordance rate of cytopathological diagnosis with histopathological diagnosis was analyzed.Results Among the 370 cases,histopathological diagnosis revealed 177 (47.84％) cancers,22 (5.95 ％) malignant tumors,16 (4.32％) suspicious malignancy,12 (3.24％) atypical cells and 143 (38.65 ％)negative findings,whereas the corresponding number for cytopathological diagnosis were 166(44.87％),10(2.70％),16(4.32％),49(13.24％)and 129(34.87％).The two diagnosis methods were correlated (P ＜ 0.001).The sensitivity of cytopathological diagnosis,histopathological diagnosis and the combinational method were 80.00％ (192/240),89.58％ (215/240) and 98.33％ (236/240),respectively.The eytopathologieal diagnosis and the histopathologieal diagnosis had a statistically significant difference in the sensitivity (P ＜ 0.05).The difference in sensitivity between the combinational method and the histopathological diagnosis was statistically significant(P ＜ 0.05).Overall,66.15％ (127/192) of the cytopathogically positive cases were precisely typed by cytopathological diagnosis.Complications during or after the operation were found in 14.59％ of cases,among which 31 had pneumothorax and 23 had bleeding in the needle passage or bloody sputum,all improving after appropriate treatment.Conclusion Percutaneous lung biopsy under CT guidance is a safe,sensitive and accurate method for diagnosis of lung diseases,and the combinational use of cytopathological diagnosis and histopathological diagnosis significantly increases the rate of diagnosis and has a favorable clinical application value.关键词
肺肿瘤/CT引导/活检/细胞学/组织病理学Key words
lung neoplasms/CT-guided/biopsy/cytology/histopathology分类
医药卫生引用本文复制引用
赵媛,赵永刚,陈昊,张智弘..CT引导下经皮肺穿刺细胞学和组织学联合检查的诊断价值[J].临床与实验病理学杂志,2016,32(12):1371-1373,1378,4.
