山东医药2017，Vol.57Issue(12)：5-7,3.DOI:10.3969/j.issn.1002-266X.2017.12.002
天津地区8577例慢性乙型肝炎病毒感染者血清标志物模式分析
Analysis of HBV serum markers in 8 577 chronically infected patients
摘要
Abstract
Objective To analyze the models and characteristics of hepatitis B virus (HBV) serum markers in patients with chronic hepatitis B from Tianjin area.Methods HBV serum markers of 8 577 patients with chronic hepatitis B from Tianjin area were detected by the electrochemical luminescence immunoassay (ECLIA).The different models of HBV serum markers were analyzed and stratified by age and gender.Results There were 18 models of HBV serum markers in this study.Model 1 (HBsAg+, anti-HBe+, anti-HBc+) (40%) and model 2 (HBsAg+, HBeAg+, anti-HBc+) (27.14%) were predominant.When stratified with age and gender, we found that the proportion was higher in 20 to 39-year-old patients of these two models (49.58%, 62.16%, respectively) and there were more males than females (P<0.05 or P<0.01).The models with both positive HBsAg and anti-HBs accounted for 5.5%.The proportion was lower in patients less than 20 years old in model 1 and model 2 (0.61%, 2.58%, respectively).Conclusions The models of HBsAg+, HBeAg+, HBcAb+ and the model of HBsAg+, HBeAb+, HBcAb+ were the main patterns of chronic hepatitis B patients in Tianjin area.The proportion was higher in 20 to 39-year-old patients of these two models and there were more males than females.关键词
慢性乙型肝炎病毒感染/血清标志物/横断面研究/天津市Key words
chronic hepatitis B virus infection/serum marker/cross-sectional study/Tianjin city分类
医药卫生引用本文复制引用
霍志晓,张世田,乔坤艳,代庆海,陆伟,侯伟..天津地区8577例慢性乙型肝炎病毒感染者血清标志物模式分析[J].山东医药,2017,57(12):5-7,3.基金项目
国家自然科学基金资助项目(30800974/81271845) （30800974/81271845）
天津市卫生局科技基金重点项目(2012KR02) （2012KR02）
天津市卫生局科技基金攻关项目(12KG118). （12KG118）
