陕西医学杂志2017，Vol.46Issue(4)：417-418,425,3.DOI:10.3969/j.issn.1000-7377.2017.04.003
PON-1基因多态性与PCI术后主要心血管事件相关性研究
Correlation between PON1 gene polymorphism and major cardiovascular events after PCI
摘要
Abstract
Objective: To investigate the risk factors influencing the prognosis of patients with coronary artery intervention, and analyze the correlation between PON-1 gene polymorphism and the major adverse cardiovascular events after PCI.Methods: 362 patients with PCI were selected, PON1 Q192R polymorphism was detected with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technology.All the patients were followed up 6 months, the incidence of MACE during the period was monitored and recorded.The correlation between PON1 gene polymorphism and MACE was analyzed.Results:The incidence of MACE after PCI was not significantly correlated with PON1 gene polymorphism.Conclusion:There is no correlation between MACE and PON1 gene polymorphism, but more high quality investigation is in need.关键词
经皮冠状动脉介入治疗/@PON-1/血小板聚集/@主要心血管事件Key words
Percutaneous Coronary Intervention/@PON1/@Major adverse cardiovascular events分类
医药卫生引用本文复制引用
辛宏,李程亮,蔡天志,张科林,张安吉..PON-1基因多态性与PCI术后主要心血管事件相关性研究[J].陕西医学杂志,2017,46(4):417-418,425,3.基金项目
陕西省教育厅基金资助项目(12JK0771) （12JK0771）
