生殖医学杂志2017,Vol.26Issue(4):324-327,4.DOI:10.3969/j.issn.1004-3845.2017.04.006
新的囊胚活检方法——囊胚活检不再纠结和繁琐
A novel method making blastocyst biopsy simple and controllable
摘要
Abstract
Blastocyst biopsy is a prerequisite for PGD & PGS and single gene disorder diagnosis.At present,zona pellucida opening and partially trophectoderm (TE) cell hatching are needed before blastocyst biopsy.It causes that blastocyst hatching time is uncertain,and the inner cell mass is in abnormal position,or blastocyst is hatched prematurely.All these bring the difficulties to blastocyst biopsy,and may also affect the final clinical outcome of biopsied blastocyst transplantation.The new blastocyst biopsy method does not need zona pellucida opening before biopsy,only utilizes the zona pellucida binding force itself to reduce the laser wound,which makes biopsy more simple and controllable,and also improves the clinical outcomes of biopsied blastocyst transfer to some extent.关键词
囊胚活检/透明带打孔/囊胚孵出/内细胞团Key words
Blastocyst biopsy/Zona pellucida opening/Blastocyst hatching/Inner cell mass引用本文复制引用
吴克良..新的囊胚活检方法——囊胚活检不再纠结和繁琐[J].生殖医学杂志,2017,26(4):324-327,4.基金项目
默克雪兰诺中国生殖医学研究基金(2015) (2015)