天然产物研究与开发2017，Vol.29Issue(2)：183-189,7.DOI:10.16333/j.1001-6880.2017.2.001
肾茶化学成分研究
Compounds from Clerodendranthus spicatus
摘要
Abstract
Two new compound,(7'S,8'S)-8-epiblechnic acid diacetate (1) and threo-2-(4-hydroxy-3,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxy-phenyl)-3-ethoxypropan-1-ol (2),along with sixteen known compounds were isolated from Clerodendranthus spicatus.Their structures were identified as 9-hydroxy-4,7-megastigmadien-3-one (3),dehydrololiolide (4),3-hydroxy-4-oxo-7,8-dihydro-β-ionone (5),3-hydroxy-7,8-dehydro-β-ionol (6),3-hydroxy-5,6-epoxy-β-ionone (7),loliolide (8),threo-2,3-bis (4-hydroxy-3-methoxyphenyl)-3-ethoxy-propan-1-ol (9),erythro-2,3-bis (4-hydroxy-3-methoxyphenyl)-3-ethoxypropan-1-ol (10),pinoresinol (11),(+)-syringaresinol (12),(+)-(7R,7'R,7"R,7'''R,8S,8'S,8''S,8'''S)-4'',4'''-dihydroxy-3,3',3'',3''',5,5'-hexame-thoxy-7,9':7',9-diepoxy-4,8'':4',8'''-bisoxy-8,8'-dineolignan-7'',7''',9'',9'''-tetraol (13),fragransins B1-B3 (14-16),sacidumol A (17),and 3',4',5,6,7-pentamethoxyflavone (18),respectively,by spectroscopic methods.Compounds 1 and 2 are new substances,where compound 1 is likely a new artifact derived from 8-epiblechnic acid.Besides,the absolute configuration of 1 was assigned by ECD calculations.In addition,compounds 3-11 and 13-17 were isolated from C.spicatus for the first time.关键词
肾茶/唇形科/量子计算/倍半萜/木脂素Key words
Clerodendranthus spicatus/Labiatae/sesquiterpenes/lignans/ECD calculations分类
医药卫生引用本文复制引用
李小珍,晏永明,程永现..肾茶化学成分研究[J].天然产物研究与开发,2017,29(2):183-189,7.基金项目
云南省南药研究协同创新中心项目 （）
