天然产物研究与开发2017,Vol.29Issue(2):240-244,5.DOI:10.16333/j.1001-6880.2017.2.010
茄病镰刀菌发酵液中环孢菌素同系物的分离纯化和鉴定
Isolation, Purification and Structural Identification of Cyclosporine Analogues from Fermentation Broth of Strain Fusarium solani sp.FIM116
摘要
Abstract
Two cyclosporine analogues were isolated and purified by solvent extraction,silica gel chromatography,reversion phase chromatography and other ways from the fermentation broth of Fusarium solani sp.FIM116.Their structures were identified as cyclosporine G and cyclosporine T by physic-chemical properties and spectroscopic data.关键词
茄病镰刀菌/环孢菌素G/环孢菌素T/分离纯化/结构鉴定Key words
Fusarium solani/cyclosporine G/cyclosporine T/isolation and purification/structural identification分类
医药卫生引用本文复制引用
杨煌建,王德森,张祝兰,唐文力,任林英,邱观荣,连云阳..茄病镰刀菌发酵液中环孢菌素同系物的分离纯化和鉴定[J].天然产物研究与开发,2017,29(2):240-244,5.基金项目
福州市科技计划(2015-G-81) (2015-G-81)
福建省化药技术重大研发平台(2014Y2001) (2014Y2001)
福州市生物制药行业技术创新中心(2016-PT-36) (2016-PT-36)