同位素2017，Vol.30Issue(1)：78-88,11.DOI:10.7538/tws.2017.30.01.0078
金属正电子核素64Cu,68Ga,86Y和89Zr的PET标记药物研究进展
Positron Emission Radiometals 64Cu, 68Ga, 86Y and 89Zr Labeled PET Drugs
陈文 1魏洪源 1周志军 1罗顺忠1
作者信息
- 1. 中国工程物理研究院核物理与化学研究所,四川绵阳621900
- 折叠
摘要
Abstract
Positron emission radiometals 64Cu,68Ga,86Y and 89Zr have different half lives and special biological properties,not only enrich the diversity of PET drugs,but also provide a new opportunity for the diagnosis and treatment of disease.In recent years,positron emission radiometals 64Cu,68Ga,86Y and 89Zr have more and more applications in the medical diagnostics of PET (positron emission tomography).64Cu has already had a significant impact in cancer hypoxia imaging.68Ga is developing rapidly in the field of diagnosis of NET (Neuroendocrine tumor) tumor.89Zr and 86Y are expected to play a role in the field of immunoPET and radioimmunotheray.This paper briefly reviews the research progress on the production and purification,solution coordination chemistry and applications of 68Ga,86Y,89Zr and 64Cu.关键词
正电子发射计算机断层显像(PET)/64Cu,68Ga,86Y,89Zr/配位化学/临床应用Key words
positron emission tomography/64Cu, 68Ga, 86Y, 89Zr/coordination chemistry/clinical application分类
医药卫生引用本文复制引用
陈文,魏洪源,周志军,罗顺忠..金属正电子核素64Cu,68Ga,86Y和89Zr的PET标记药物研究进展[J].同位素,2017,30(1):78-88,11.
