外科理论与实践2017，Vol.22Issue(2)：134-138,5.DOI:10.16139/j.1007-9610.2017.02.011
胰腺囊性肿瘤术前恶性预测(附342例报告)
Preoperative prediction of malignancy of pancreatic cystic neoplasm: a report of 342 cases
摘要
Abstract
Objective To evaluate the use of clinical features, preoperative examination and imaging for predicting malignancy in pancreatic cystic neoplasm (PCN). Methods We included in the retrospective study 342 patients with PCN in our hospital from January 2003 to April 2015. Chi-square and t test were used to analyze the potential factors predicting in malignancy of PCN. Logistic regression of multivariable was applied with the factors P<0.20 for independent risk factors of malignancy. Results There were several factors which would be helpful to predict the malignant PCN including the pre-sent symptoms, male, older than 55, with history of diabetes mellitus or hypertension, very elevation of CA19-9 or CEA, the cyst located at the head, neck or uncinate process of the pancreas, pancreatic duct dilation, solid component and cyst diameter of 3 cm or more. The present symptoms, history of diabetes mellitus, elevation of CA19-9 or CEA, solid compo-nent of cyst and cyst diameter of 3 cm or more were all independent risk factors to predict malignancy of PCN. Cytological result of EUS-FNA helped the prediction of malignancy of PCN. Conclusions The patients with presence of symptoms, diabetes mellitus, elevation of CA19-9 or CEA, solid component of cyst and cyst diameter of 3 cm or more would be useful for preoperative prediction of malignant PCN. EUS-FNA is a valuable tool of preoperative prediction of malignant PCN.关键词
胰腺囊性肿瘤/术前/恶性预测/超声内镜引导细针穿刺Key words
Pancreatic cystic neoplasm/Preoperative/Prediction of malignancy/Endoscopic ultrasound-guided fine-needle aspiration分类
医药卫生引用本文复制引用
洪理文,沈柏用,彭承宏,赵治锋,张俊,许志伟,王建承,吴卫泽,费健,邓侠兴,钟捷..胰腺囊性肿瘤术前恶性预测(附342例报告)[J].外科理论与实践,2017,22(2):134-138,5.基金项目
国家自然科学基金(81670581,81600501) （81670581,81600501）
