中国医疗设备2017，Vol.32Issue(4)：83-86,4.DOI:10.3969/j.issn.1674-1633.2017.04.022
肥胖细胞型星形细胞瘤的MRI表现探讨
Investigation of Magnetic Resonance Imaging Manifestations of Gemistocytic Astrocytoma
摘要
Abstract
Objective To preliminarily investigate the MRI manifestations and imaging features of gemistocytic astrocytoma (GemA) so as to improve the level of recognition and diagnosis of the disease. Methods The clinical and imaging data of 13 patients with GemA, diagnosed via surgery as well as pathology from October 2010 to December 2015, were reviewed retrospectively. All patients were performed by both plain and enhanced MRI scanning. 9 cases of them still were performed with magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), arterial spin labeling (ASL) and perfusion weighted imaging (PWI) scanning,along with 1 case through susceptibility weighted imaging (SWI) sequence. Then the related MRI imaging features were analyzed and summarized.Results 13 GemA patients were all solitary lesions and located at supratentorial sites, with 10 cases located in the frontal lobe, 2 cases in temporal lobe, 1 case in parietal lobe. Of these 13 cases, 8 cases were confined to single lobe lesion, 5 cases were involved in multiple lobe which invaded the opposite brain tissue through corpus callosum; 8 cases had unclear boundary, the other 5 cases presented with clear boundary; 7 cases showed multiple and various sizes of cystic lesions in solid part. The solid portions of the tumor demonstrated slightly hypo intense on T1WI, slightly hyper intense on T2WI and DWI, and obviously uneven enhancement in moderate or above level; MRS characterized that Cho (choline) peak increased, NAA (N-acetyl aspartic acid) peak decreased and Cr (creatine) peak was basically stable; ASL and PWI presented hypoperfusion, DTI showed lateral cortical fiber bundle was sparser obviously than contralateral side.Conclusion MRI manifestations of GemA were mainly single, located in the frontal lobe, much unclear boundary with cystic change inside, invading the opposite tissues through corpus callosum, and uneven enhanced in moderate or above level to solid elements of tumor. What's more, MRS, DTI, ASL, SWI and PWI could be combined with MRI to help diagnose the disease.关键词
肥胖细胞/星形细胞瘤/磁共振成像/磁共振波谱成像/弥散加权成像Key words
gemistocyte/astrocytoma/MRI/magnetic resonance spectroscopy/diffusion weighted imaging分类
医药卫生引用本文复制引用
吴玉珍,钟群,林金贵,吴慧敏..肥胖细胞型星形细胞瘤的MRI表现探讨[J].中国医疗设备,2017,32(4):83-86,4.基金项目
南京军区联勤部课题(12MA097). （12MA097）
