中国动脉硬化杂志2017，Vol.25Issue(3)：259-263,5.
首发未服药抑郁症患者血清非高密度脂蛋白胆固醇水平及相关因素分析
Analysis of serum non-high density lipoprotein cholesterol level and related factors in first-episode drug-native patients with depressive disorder
摘要
Abstract
Aim To explore the serum non-high density lipoprotein cholesterol (non-HDLC) level in patients with depression and analyze the related factors.Methods 150 depression patients were tested in Mfiliated Kailuan Mental Health Center,North China University of Science and Technology from June 2014 to November 2015,testing the total cholesterol (TC),triglyceride (TG),high density lipoprotein cholesterol (HDLC),low density lipoprotein cholesterol (LDLC),and measuring the depressive symptoms through the self-rating depression scale (SDS).Using SPSS 17.0 software,the data was tested by independent sample t test,single factor variance analysis,partial correlation analysis and stepwise multiple regression analysis.Results There was statistical significance about differences between depression and healthy people on the serum non-HDLC level (P＜0.05).There was statistical significance about the differences on the serum non-HDLC level of depression in different gender,age,education level and depression severity (P＜0.05).After controlling the gender,age and education level,the standard score of SDS in depression had a significantly negative correlation with the TC,TG,LDLC and non-HDLC level (P＜0.05).The standard score of SDS in depression had significantly negative predictive power on the non-HDLC level (3 =-0.682,P＜0.05).Conclusion Depression is related to the non-HDLC level,and the risk and mechanism of cardiovascular disease in patients with depressive disorder should be paid attention to.关键词
抑郁症/非高密度脂蛋白胆固醇/心血管疾病Key words
Depressive disorder/Non-high density lipoprotein cholesterol/Cardiovascular disease分类
医药卫生引用本文复制引用
苑杰,郭鑫,王萌,刘昊,王静..首发未服药抑郁症患者血清非高密度脂蛋白胆固醇水平及相关因素分析[J].中国动脉硬化杂志,2017,25(3):259-263,5.基金项目
国家自然科学基金资助项目(81201048) （81201048）
河北省医学科学研究重点课题计划立项项目(20150050 （）
20160218) （）
河北省中医药管理局中医药类科研计划课题(2016079) （2016079）
国家卫生计生委重点实验室课题(20150006) （20150006）
华北理工大学研究生创新项目(2017S04) （2017S04）
