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血管平滑肌细胞自噬与血管钙化关系的研究进展

蒲江

中国动脉硬化杂志2017,Vol.25Issue(3):321-324,4.
中国动脉硬化杂志2017,Vol.25Issue(3):321-324,4.

血管平滑肌细胞自噬与血管钙化关系的研究进展

The recent advances between vascular smooth muscle cells autophagy and vascular calcification

蒲江1

作者信息

  • 1. 西南医科大学附属医院肾病内科,四川省泸州市646000
  • 折叠

摘要

Abstract

Autophagy is a highly conserved catabolisml process of self-degradation responsible for maintaining cellular homeostasis.Vascular calcification is common in many diseases such as atherosclerosis,diabetes and end-stage renal disease,which is a major risk factor of cardiovascular mortality.Today the effective therapy for vascular calcification is still unavailable.Recent studies indicate that vascular smooth muscle cells (VSMCs) autophagy may play an important role in vascular calcification by regulating the activity of self-degradation and the transdifferentiation process of VSMCs to osteogenic phenotype.This article briefly reviews the recent advances between VSMCs autophagy and vascular calcification.

关键词

血管平滑肌细胞/自噬/血管钙化

Key words

Vascular smooth muscle cells/Autophagy/Vascular calcification

分类

医药卫生

引用本文复制引用

蒲江..血管平滑肌细胞自噬与血管钙化关系的研究进展[J].中国动脉硬化杂志,2017,25(3):321-324,4.

中国动脉硬化杂志

OACSTPCD

1007-3949

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