中国感染控制杂志2017，Vol.16Issue(1)：58-61,65,5.DOI:10.3969/j.issn.1671-9638.2017.01.013
ICU多重耐药菌目标性监测与干预效果分析
Efficacy of targeted monitoring and intervention on multidrug-resistant organisms in intensive care units
摘要
Abstract
Objective To understand the status of infection with multidrug-resistant organisms (MDROs) in intensive care units(ICUs),and evaluate the intervention efficacy of targeted monitoring.Methods Prospective study was adopted,patients who were admitted to ICUs in 2014-2015 were selected (January-December 2014 was as preintervention stage,January-December 2015 was as intervention stage),trend of MDRO infection before and after intervention were compared and analyzed.Results Before and after intervention,297 and 217 strains of MDROs were isolated respectively,except carbapenem-resistant Pseudomonasaeruginosa (CRPA),the isolated strains of carbapenem-resistant Acinetobacterbaunannii (CRAB),carbapenem-resistant Enterobacteriaceae (CRE),methicillin-resistant Staphylococcus aureus(MRSA),and vancomycin-resistant Enterococcus (VRE) declined after intervention.MDRO infection rate declined from 7.17 ％ before intervention to 3.88％ after intervention,infection rate of CRAB and CRE after intervention were both lower than before intervention (both P＜0.05);MDRO infection rates in general ICU and internal medicine ICU increased from 8.75％ and 7.84‰ before intervention to 4.39‰ and 2.28％ after intervention,respectively (both P＜0.05).After taking comprehensive intervention measures,compliance to prevention and control measures,such as ordering rate of doctor's advice on contact isolation for 24 hours,hand hygiene,health care workers' awareness all enhanced significantly(all P＜0.05).Conclusion Targeted monitoring and intervention measures can reduce isolation rate of MDROs in ICUs.关键词
重症监护病房/多重耐药菌/目标性监测/干预Key words
intensive care unit/multidrug-resistant organism/targeted monitoring/intervention分类
医药卫生引用本文复制引用
陈亚男,刘菁,田丽梅,刘善善,潘立业,刘婷,吴惠毅..ICU多重耐药菌目标性监测与干预效果分析[J].中国感染控制杂志,2017,16(1):58-61,65,5.基金项目
连云港市科技局资助项目(SH1529) （SH1529）
