局解手术学杂志2017，Vol.26Issue(3)：185-188,4.DOI:10.11659/jjssx.11E016046
Solitaire支架机械取栓与选择性动脉溶栓治疗急性脑梗死的疗效比较
Comparative study of clinical efficacy between the Solitaire mechanical thrombectomy and selective arterial thrombolysis in treatment of acute cerebral infarction
摘要
Abstract
Objective To investigate the clinical safety and efficacy of mechanical thrombectomy(MT) with Solitaire stent compared with the selective intra-arterial thrombolysis (IAT) in the treatment of acute cerebral infarction.Methods Totally 82 cases patients with severe acute ischemic stroke caused by middle cerebral artery stenosis from January 2014 to May 2016 in the stroke treatment center of the first people's Hospital in ZunYi city who were applied with the mechanical thrombectomy or the selective intra-arterial thrombolysis was included,and a comparative analysis was conducted on the mTICI rating to assess the interventional recanalization,the NIHSS score after the treatment,bleeding rate,and conditions of neurological functional recovery 90 days after operation.Results There were 42 cases applied with the mechanical thrombectomy (MT group),40 cases applied with the intra-arterial thrombolysis (IAT group).The total effective rate reached 85.70％ in the MT group and 62.50％ in the IAT group,the difference was significant (P ＜ 0.05).Compared with NIHSS score before operation,the score after the treatment showed a decreased trend.And the NIHSS score of MT group was better than that of the IAT group in a week after the treatment (P ＜ 0.05).The bleeding rate was lower in the MT group with statistically significant difference (P ＜ 0.05).Conclusion Compared to IAT,MT can provide broader time window,higher recanalization rate and better outcome in patients with severe acute ischemic stroke.关键词
急性脑梗死/Solitaire支架机械取栓/选择性动脉溶栓/疗效Key words
ischemic cerebral infarction/Solitaire mechanical thrombectomy/selective intra-arterial thrombolysis/therapeutic efficacy分类
医药卫生引用本文复制引用
熊波,李航,史树贵,高建军..Solitaire支架机械取栓与选择性动脉溶栓治疗急性脑梗死的疗效比较[J].局解手术学杂志,2017,26(3):185-188,4.基金项目
遵义市科学技术局资助[遵义市合作字(2011)15号] （2011）
