中国康复理论与实践2017，Vol.23Issue(4)：446-448,3.DOI:10.3969/j.issn.1006-9771.2017.04.018
选择性β1受体阻滞剂对高血压患者运动耐力的影响
Effect of Selective beta-1 Adrenoreceptor Blocker on Exercise Tolerance in Patients with Hypertention
摘要
Abstract
Objective To explore the effect of selective beta-1 adrenoreceptor blocker on exercise tolerance in patients with hyperten-sion. Methods From May, 2015 to May, 2016, 72 patients with hypertension were divided into two groups, according to whether taking the selective beta-1 receptor blocker. Group A (n=35) took the selective beta-1 receptor blocker two weeks before cardiopulmonary exercise, while group B (n=37) did not take anything at the same time. The exercise tolerance was compared between two groups. Results The maxi-mal systolic blood pressure, peak heart rate, one-minute heart rate after exercise (HR1) and rate-pressure product were lower in group A than in group B (t>2.012, P<0.05), however, the recovery value of HR1 was higher in group A than in group B (t=2.100, P<0.05). There was no difference in both peak power and peak oxygen uptake between two groups (t<0.689, P>0.05). Conclusion The selective beta-1 adrenore-ceptor blocker could reduce myocardial oxygen consumption, and improve vagus nerve activity, but did not reduce exercise tolerance in pa-tients with hypertension.关键词
高血压病/β1受体阻滞剂/心肺运动试验Key words
hypertension/selective beta-1 adrenoreceptor blocker/cardiopulmonary exercise testing分类
医药卫生引用本文复制引用
李寿霖,封丽红,陈思远,杨祖福,张焱,刘杰,杨威,刘立君,郑志昌,林伟,王晓荣,王国栋..选择性β1受体阻滞剂对高血压患者运动耐力的影响[J].中国康复理论与实践,2017,23(4):446-448,3.基金项目
中央级公益性科研院所基本科研业务费专项资金项目(No.2015CZ-40). （No.2015CZ-40）
