中国临床药理学杂志2017，Vol.33Issue(5)：461-462,2.DOI:10.13699/j.cnki.1001-6821.2017.05.021
1例阿仑膦酸钠致老年女性骨质疏松患者的癌胚抗原反复增高
Repeated elevation of carcinoembryonic antigen induced by alendronate sodium in an elder osteoporosis woman
摘要
Abstract
Objective One case of repeated elevation of carcinoembryonic antigen (CEA) induced by alendronate sodium in an elder osteoporosis woman was introduced to draw physicians'attention.Methods One elderly women with osteoporosis was treated with oral alendronate sodium 70 mg,once a week.The serum CEA was detected at an regular interval.The relationship between CEA elevation and alendronate sodium therapy was evaluated with Naranjo's assessment scale.Results and conclusion The serum level of CEA was repeatedly observed to gradually increase several weeks after treatment,while gradually decline after discontinuing the medication.The elevation of CEA took placed in a sequential manner in relation to the administration of alendronate sodium.Naranjo's assessment gave a total score of 8 points,indicating that CEA may be associated with the use of alendronate sodium.关键词
阿仑膦酸钠/癌胚抗原/骨质疏松Key words
alendronate sodium/carcinoembryonic antigen/osteoporosis分类
医药卫生引用本文复制引用
寿张轩,边平达,金雪..1例阿仑膦酸钠致老年女性骨质疏松患者的癌胚抗原反复增高[J].中国临床药理学杂志,2017,33(5):461-462,2.基金项目
浙江省医药卫生平台重点资助计划基金资助项目(2016ZDA002) （2016ZDA002）
浙江省人民医院优秀青年人员科研启动基金资助项目(zry2015C002) （zry2015C002）
