中国内镜杂志2017，Vol.23Issue(4)：18-25,8.DOI:10.3969/j.issn.1007-1989.2017.04.004
腹腔镜和开腹手术治疗中国老年宫颈癌疗效的Meta分析
Comparison of laparoscopic versus laparotomic operation for cervical carcinoma in elderly Chinese women: a meta-analysis
摘要
Abstract
Objective To compare the curative effect of laparoscopic and laparotomic operation for elderly Chinese women with cervical cancer. Methods The randomized controlled trials (RCT) and case controlled trials (CCT) were collected by searches of WanFang database, CNKI, VIP, China Biology Medicine (CBM) , PubMed. Data were extracted from these trials and data analysis was performed by RevMan 5.2.9. Results There were no RCTs, however, a total of 10 CCTs met the inclusion criteria and had data extracted for this review. The baseline characteristics of the laparoscopic group were similar to those of the laparotomic group. Comparing to laparotomic group, the laparoscopic group have longer operation time (MD =32.60, 95%CI: 5.65~59.55, P = 0.020), less amount of bleeding (MD = -94.01, 95%CI: -130.65 ~ -57.37, P = 0.000), smaller number of lymph node dissection(MD = 1.69, 95%CI: 0.67 ~ 2.72, P = 0.001), earlier anus exhaustion (MD=-17.09, 95%CI: -21.19 ~ -12.98, P = 0.000) and shorter hospital stays (MD = -4.30, 95%CI: -5.57 ~ -3.02, P = 0.000). There was significant difference between the two groups. But there was no statistical significance in postoperative indwelling catheter time (MD = -0.67, 95%CI: -1.92 ~ 0.58, P = 0.290) and surgical complications incidence (OR=0.62, 95%CI: 0.27 ~ 1.42, P = 0.260) between the two groups. Conclusion Laparoscopic management has the advantages of less traumatic and recovered quickly, and did not increase the incidence of complications. Laparoscopic operation is an ideal procedure for elderly Chinese women with cervical carcinoma.关键词
腹腔镜手术/开腹手术/老年妇女/宫颈癌/Meta分析Key words
laparoscopy/laparotomy/elderly women/cervical carcinoma/Meta-analysis分类
医药卫生引用本文复制引用
赵鲁文,于爱军,张玉娟,宋晓莉,毛淑芳..腹腔镜和开腹手术治疗中国老年宫颈癌疗效的Meta分析[J].中国内镜杂志,2017,23(4):18-25,8.基金项目
河北省承德市科学技术研究与发展计划(No :20123122) （No :20123122）
