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一种血细胞分离机不同转速对外周血造血干细胞采集的影响

李清 廖和东 蒋迷 韩风 杨泽松 李招权

中国输血杂志2017,Vol.30Issue(2):188-190,3.
中国输血杂志2017,Vol.30Issue(2):188-190,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.02.027

一种血细胞分离机不同转速对外周血造血干细胞采集的影响

Effects of different centrifugal speed in one blood cell separator on peripheral blood stem cell collection

李清 1廖和东 1蒋迷 1韩风 1杨泽松 1李招权1

作者信息

  • 1. 重庆医科大学附属第一医院 血液科,重庆 400016
  • 折叠

摘要

Abstract

Objective To investigate the effects of different centrifugal speed in one blood cell separator on peripheral blood stem cell collection.Methods 229 peripheral blood stem cell collection cases were divided into 1500,1550,1600,1650,1700 and 1750r/min groups.Then WBC,Hct,Plt,MNC and CD34+ cell proportion of collections were detected.The differences between groups were statistically analyzed.Results The results showed that WBC and Plt were raised but HCT,MNC and CD34+ cell proportion reduced gradually in collections with rising centrifugal speed.There was statistical significance (P<0.05 or P<0.01) in 1 650 r/min group compared with 1 500 r/min group except for WBC (P>0.05).Conclusion This shows that the difference in centrifugal speed plays a certain extent on peripheral blood stem cell collection.To ensure optimal collection effect,lower centrifugal speed [(1 500-1 600) r/min] is appropriate according to clinical condition.

关键词

外周血造血干细胞采集/转速/血细胞分离机

Key words

peripheral blood stem cell collection/centrifugal speed/blood cell separator

分类

医药卫生

引用本文复制引用

李清,廖和东,蒋迷,韩风,杨泽松,李招权..一种血细胞分离机不同转速对外周血造血干细胞采集的影响[J].中国输血杂志,2017,30(2):188-190,3.

中国输血杂志

OACSTPCD

1004-549X

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