中国药理学通报2017,Vol.33Issue(4):450-454,5.DOI:10.3969/j.issn.1001-1978.2017.04.002
嘌呤受体在神经元和神经胶质细胞间信息传递中的作用
Function of purinergic receptorsin communication between neurons and glial cells
摘要
Abstract
The function of the nervous system is largely determined by the communication between neurons and glial cells.The interaction of complex signaling pathways between neurons and glial cells involves in a variety of signaling molecules.Purines and the purinergic receptors play a crucial role in the process of the interaction.For a long time, the study on the central nervous system is mainly focused on neurons, while glial cells are mainly used as support cells or in response to brain injury to provide a guiding role.The latest research shows that glial cells play an important role in the occurrence and development of nervous system diseases.We will summarize the function of purinergic receptors in the interaction of neurons and glial cells and in neurological diseases.关键词
嘌呤受体/嘌呤核苷酸/神经元/神经胶质细胞/信息传递/神经系统疾病Key words
purinergic receptors/purine nucleotides/neuron/glial cell/communication/neurological diseases分类
医药卫生引用本文复制引用
盛璇,李桂林..嘌呤受体在神经元和神经胶质细胞间信息传递中的作用[J].中国药理学通报,2017,33(4):450-454,5.基金项目
国家自然科学基金课题(No 81560219, 81200853) (No 81560219, 81200853)
江西省青年科学家(井冈之星)培养对象(No 20153BCB23030) (井冈之星)