中国药理学与毒理学杂志2017，Vol.31Issue(3)：279-286,8.DOI:10.3867/j.issn.1000-3002.2017.03.012
紫苏叶化学成分、抗炎作用及其作用机制研究进展
Research progress in chemical constituents, anti-inflammatory effect and mechanism of Folium Perillae
摘要
Abstract
Folium Perillae (FP) is a traditional Chinese materia medica, which has been used for treating inflammatory diseases. In order to clarify the material basis of FP' s pharmacological activity and anti-inflammatory mechanism, we presented a review about some of the primary chemical components in FP, such as volatile oils, flavonoids, anthocyanins, phenolic acids, glycosides, triterpenes and steroids, and about the anti-inflammatory activity of FP extract and its major mechanism, such as regulating the viability and function of innate immune cells, controlling the balance of helper T cells, based on related research in recent years. This study aims to provide reference for further research and development of new drugs based on FP.关键词
紫苏叶/化学成分/炎症Key words
Folium Perillae/chemical constituents/inflammation分类
医药卫生引用本文复制引用
杨慧,马培,林明宝,侯琦..紫苏叶化学成分、抗炎作用及其作用机制研究进展[J].中国药理学与毒理学杂志,2017,31(3):279-286,8.基金项目
国家自然科学基金(81473398) （81473398）
中国医学科学院医学与健康创新工程-重大协同创新项目(2016-I2M-2-006) The project supported by National Natural Science Foundation of China (81473398) （2016-I2M-2-006）
and CAMS Initia?tive for Innovative Medicine (CAMS-I2M:2016-I2M-2-006) （CAMS-I2M:2016-I2M-2-006）
