中国医学科学院学报2017，Vol.39Issue(1)：95-100,6.DOI:10.3881/j.issn.1000-503X.2017.01.016
第3代双源CT低管电压70 kV联合高级模拟迭代重建在结肠CT成像中的应用
Application of Low Tube Voltage 70 kV and Advanced Modeled Iterative Reconstruction in the Third-generation Dual-source CT to CT Colonography
摘要
Abstract
Objective To explore the feasibility of reducing radiation dose of CT colonography (CTC) while preserving image quality using the third-generation dual-source CT at 70 kV tube voltage with advanced modeled iterative reconstruction (ADMIRE).Methods This prospective study consecutively included 53 patients.All patients underwent CTC at 120 kV in supine position with filtered back projection reconstruction and at 70 kV in prone position with ADMIRE with the same scan range.Radiation dose and image quality were compared between these two protocols.Results CT dose index volume, dose-length product, and effective dose of 70 kV were (1.47 ± 0.23) mGy, (68.85 ± 13.82) mGy.cm, and (1.03 ± 0.21) mSv, respectively,which were significantly lower than 120 kV mode [(2.96 ± 0.61) mGy (t =25.356, P =0.000), (136.97 ±32.77) mGy.cm (t =22.246, P =0.000), and (2.05 ± 0.49) mSv (t =22.293, P =0.000)] Signal to noise ratio of 70 kV with ADMIRE was 3.60 ± 0.58, which was obviously higher than that of 120 kV as 2.34±0.47 (t=-18.036, P=0.000).Noise of 70 kV with ADMIRE was (11.81±1.93) HU, which was obviously lower than that of 120 kV as (14.39 ±2.57) HU (t =7.856, P =0.000).The κ value of two radiologists' overall subjective image score was 0.843 (P =0.000).For 2D images, the noise score of 70 kV with ADMIRE was significantly lower (Z =325.000, P =0.000) and the overall image quality was significantly higher (Z =78.000, P =0.001) compared with 120 kV;however, the sharpness had no significant difference.All scores ranged from 4 to 5.For 3 D virtual endoscopy, the overall image quality of 70 kV with ADMIRE and 120 kV was not significantly different (Z =4.000, P =0.059), and all scores ranged from 4 to 5.Conclusion CTC at 70 kV tube voltage combined with ADMIRE can remarkably reduce the radiation dose while maintaining imaging quality than 120 kV at third-generation dual-source CT.关键词
结肠CT/低管电压/高级模拟迭代重建/辐射剂量/图像质量Key words
CT colonography/low tube voltage/advanced modeled iterative reconstruction/radiation dose/image quality分类
医药卫生引用本文复制引用
刘婧娟,潘卫东,薛华丹,李斌,王萱,孙昊,王沄,刘炜,金征宇..第3代双源CT低管电压70 kV联合高级模拟迭代重建在结肠CT成像中的应用[J].中国医学科学院学报,2017,39(1):95-100,6.基金项目
国家临床重点专科建设项目(2014)和卫生公益性行业科研专项项目(201402019) Supported by the National Key Clinical Specialist Construction Programs of China (2014) and the Health Industry Special Scientific Research Project (201402019) （2014）
