摘要
Abstract
Objective To explore the risk factors which may lead to the secondary infection in the severe acute pancreatitis (SAP) patients and provide the evidences of reducing the secondary infection. Method Divided 118 SAP patients who were admitted in our hospital intensive care unit (ICU) from May 2013 to May 2015 into the infection group (41 cases) and non-infection group (77cases) according to whether infected during the treatment. 13 clinical indexes including gender, age, etiological factor, type 2 diabetes, surgical treatment, indwelling drainage tube, hypoxemia, acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) score, number of organ failure, mechanical ventilation time, fasting time, serum amylase level and blood calcium level were retrospectively analyzed and compared between two groups. Single factor analysis was applied firstly for all the indexes above, and the indexes which showed the significant difference were selected into the Logistic regression model and analyzed the risk factors of SAP concurrent infection. Result There were no significant differences in gender, age, etiological factor, type 2 diabetes and indwelling drainage tube between the two groups (P > 0.05). There were statistical differences in surgical treatment, hypoxemia, APACHE Ⅱ score, number of organ failure, mechanical ventilation time, fasting time, serum amylase level and blood calcium level (P < 0.05). Result of Logistic regression analysis showed that surgical treatment, hypoxemia, high APACHEⅡ scores, multiple organ failure, long-term mechanical ventilation and long-term fasting were the risk factors causing infection in SAP patients. Conclusion High APACHE Ⅱ score on admission, multiple organ dysfunction and hypoxemia provide the tips for seconary infection in SAP patients. Surgery applied in early time of SAP, long-term mechanical ventilation and long-term fasting increase the risk of infection.关键词
重症急性胰腺炎/继发感染/危险因素Key words
Sever acute pancreatitis/Secondary infection/Risk factors
