中国药业2017，Vol.26Issue(5)：49-51,3.DOI:10.3969/j.issn.1006-4931.2017.05.014
参芪十一味颗粒预防131I治疗分化型甲状腺癌所致骨髓抑制临床研究
Shenqi Shiyiwei Granules on Preventing Bone Marrow Suppression Induced by 131I in Differentiated Thyroid Cancer
谢慧梁 1高洪波 1刘海春 1张晓勇 1邵玉军1
作者信息
- 1. 中国核工业北京四○一医院核素诊疗中心,北京 102413
- 折叠
摘要
Abstract
Objective :To observe and analyze the clinical effect of Shenqi Shiyiwei Granules in preventing bone marrow suppression in-duced by 131I in differentiated thyroid cancer. Methods 300 patients with differentiated thyroid cancer who underwent surgical treatment from June 2014 to June 2016 in the hospital were selected and divided into the control group and the study group in accordance with the random number table method, 150 cases in each group. The control group was given 131I treatment, and on this basis, the study group based was given Shenqi Shiyiwei Granules. The neutrophils and white blood cell levels in the two groups were observed and com-pared. Results There was no significant difference in neutrophils and white blood cell count between the two groups before treatment ( P > 0. 05 ) . After 4 and 8 weeks of treatment, the neutrophils and white blood cell count of the study group were significantly higher than those of the control group ( P < 0. 05 ) . The incidence of adverse reactions was 16. 67% in the study group and 13. 33% in the control group, the difference was not statistically significant ( P > 0. 05 ) . Conclusion Shenqi Shiyiwei Granules in preventing bone mar-row suppression induced by 131I in differentiated thyroid cancer has clear effect, it is better to prevent white blood cells and granulo-cytes, which is worthy of clinical promotion.关键词
参芪十一味颗粒/131I/分化型甲状腺癌/骨髓抑制/疗效Key words
Shenqi Shiyiwei Granules/131I/differentiated thyroid carcinoma/bone marrow suppression/efficacy分类
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谢慧梁,高洪波,刘海春,张晓勇,邵玉军..参芪十一味颗粒预防131I治疗分化型甲状腺癌所致骨髓抑制临床研究[J].中国药业,2017,26(5):49-51,3.
