摘要
Abstract
Objective To investigate the clinical efficacy of Latamoxef in treating acute urinary tract infection. Methods Totally 80 pa-tients with acute urinary tract infection from September 2014 to September 2016 were randomly divided into the treatment group and the control group,40 cases in each group. The treatment group was given intravenous infusion of Latamoxef 2. 0 g,2 times /d;the con-trol group was given intravenous ceftriaxone 2. 0 g,2 times/d. Both groups were treated for 14 d,and the efficacies in the two group were evaluated after treatment. Results At the 4 d of medication and 1,7 d after treatment,the effective rates were 90. 00%,97. 50%and 97. 50% in the treatment group,which were significantly higher than 67. 50%,75. 00% and 75. 00% in the control group (p < 0. 05);the effective rate of bacteriology was 94. 74%,97. 37% and 97. 37% in the treatment group,which were significantly higher than 71. 05%,73. 68% and 73. 68% in the control group(p < 0. 05). After medication,the levels of plasma procalcitonin, C-reactive protein and lipopolysaccharide in the treatment group were significantly lower than those in the control group(p < 0. 05);urine culture showed that the sensitivity of the cephalosporin was the highest(97. 37%);there was no significant difference in the inci-dence of adverse reactions between the two groups(p > 0. 05). Conclusion Latamoxef in treating acute urinary tract infection is effec-tive and safe,which can be used as a clinical optimal treatment.关键词
拉氧头孢/急性尿路感染/临床疗效/安全性/细菌学疗效Key words
Latamoxef/urinary tract infection/clinical efficacy/safety/bacteriological effect分类
医药卫生
