中国卒中杂志2017，Vol.12Issue(4)：314-319,6.DOI:10.3969/j.issn.1673-5765.2017.04.005
大脑后动脉偏侧优势对同侧大脑中动脉病变卒中严重程度及预后的影响
Influence of Posterior Cerebral Artery Laterality on the Prognosis and Severity of Stroke in Patients with Middle Cerebral Artery Stroke
张丹丹 1宋波 1赵璐 1高远 1张锐 1方慧 1刘凯 1孙石磊 1许予明1
作者信息
- 1. 450052 郑州 郑州大学第一附属医院神经内三科
- 折叠
摘要
Abstract
Objective To explore the influence of the posterior cerebral artery laterality (PCAL) on the middle cerebral artery (MCA) M1 section severe stenosis or infarct size after occlusion, stroke severity and short-term prognosis. Methods A total of 161 patients with acute ischemic stroke with MCA M1 section severe stenosis (rate of stenosis 70%-90%) or occlusion were included and divided into PCA laterality positive and negative group from Jan 2010 to Nov 2015. The baseline clinical data and modified Rankin Scale (mRS) at 3 months follow-up were compared between the two groups. Results Among the 161 patients, 76 patients presenting PCAL positive and 85 patients presenting negative. In the PCAL positive group, the stroke history was less (P=0.021); diffusion weighted imaging-Alberta Stroke Programme Early CT Score (DWI-ASPECTS) was higher (P=0.045);National Institutes of Health Stroke Scale (NIHSS) score at discharge (P=0.009) and mRS score at 3 months were lower (P=0.002); the short-term prognosis was better, which had significant difference. In the Logistic regression analysis, the NIHSS score at admission [OR (odds ratio) 1.266, 95%CI (confidence interval) 1.139-1.407, P<0.01] was the independent predictive factor of poor prognosis, and the PCAL positive (OR 0.355, 95%CI 0.146-0.864, P=0.022) was the predictive factor of good prognosis. Conclusion The smaller infarct size may suggest better short-term prognosis of patients with acute ischemic stroke caused by MCA severe stenosis or occlusion.关键词
脑梗死/大脑中动脉/大脑后动脉/侧支循环/预后Key words
Cerebral infarction/Middle cerebral artery/Posterior cerebral artery/Collateral circulation/Prognosis引用本文复制引用
张丹丹,宋波,赵璐,高远,张锐,方慧,刘凯,孙石磊,许予明..大脑后动脉偏侧优势对同侧大脑中动脉病变卒中严重程度及预后的影响[J].中国卒中杂志,2017,12(4):314-319,6.
