中华临床免疫和变态反应杂志2017，Vol.11Issue(1)：32-36,5.DOI:10.3969/j.issn.1673-8705.2017.01.006
微小RNA在系统性红斑狼疮中的作用
Role of microRNA in Systemic Lupus Erythematosus
摘要
Abstract
Systemic lupus erythematosus (SLE) is one of autoimmune diseases, caused by multiple factors.Many organ systems are damaged a large number of autoantibodies in SLE patients.The pathogenesis of SLE may be related with several candidate genes, which make SLE becoming a complex polygenic disease.The pathogenic factors of SLE change with regions and races, and not everyone having SLE susceptibility genes will develop this disease.In recent years, the connection between SLE and epigenetic regulation has got increasing attention because of the development of epigenetics.This article reviewed the relationship between microRNA and SLE,and summarized associated reports.关键词
微小RNA/红斑狼疮,系统性/表观遗传学Key words
microRNA/lupus erythematosus/systemic/epigenetics分类
医药卫生引用本文复制引用
赵静,王静..微小RNA在系统性红斑狼疮中的作用[J].中华临床免疫和变态反应杂志,2017,11(1):32-36,5.基金项目
内蒙古自然科学基金(2011MS1164),内蒙古医科大学青年创新基金(YKD2014QNCX020) （2011MS1164）
