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虫草保健品中13种核苷类成分的UHPLC-ESI-MS/MS定量分析及评价

宗时宇 韩涵 段然 张彤 王冰 董婷霞 詹华强

中药材2016,Vol.39Issue(10):2264-2267,4.
中药材2016,Vol.39Issue(10):2264-2267,4.DOI:10.13863/j.issn1001-4454.2016.10.027

虫草保健品中13种核苷类成分的UHPLC-ESI-MS/MS定量分析及评价

Quantitative Analysis and Evaluation of 13 Nucleosides in Cordyceps Health Care Products by UHPLC-ESI-MS/MS

宗时宇 1韩涵 1段然 2张彤 1王冰 1董婷霞 2詹华强2

作者信息

  • 1. 上海中医药大学,上海201203
  • 2. 香港科技大学,香港
  • 折叠

摘要

Abstract

Objective:To investigte the nucleoside compounds from eight kinds of common Cordyceps health care products which were sold in Hongkong and mainland markets.Methods:A combination of ultrasonic extraction in an ice bath and UHPLC-ESI-MS/MS analysis method were used for fast simultaneous determination of 13 nucleosides in the health care products of Cordyceps.Results:The content of targeted nucleoside compounds in health care products were significantly higher than natural medicinal materials of Cordyceps sinensis.The components of health care products mostly were Cordyceps sinensis mycelium powder,rather than from the natural medicinal materials of Cordyceps sinensis by crushing and processing directly.Conclusion:To determine the nucleosides components in Cordyceps,and compared the quality of health care products which were made from the medicinal materials and mycelium of Cordyceps sinensis in the market,which results may reflect the differences between nucleosides types and contents which have sold in the market of Cordyceps health care products.

关键词

冬虫夏草/菌丝体/保健品/核苷类/UHPLC-ESI-MS/MS

Key words

Cordyceps sinensis (Berk.) Sacc./Mycelium/Health care products/Nucleosides/UHPLC-ESI-MS/MS

分类

医药卫生

引用本文复制引用

宗时宇,韩涵,段然,张彤,王冰,董婷霞,詹华强..虫草保健品中13种核苷类成分的UHPLC-ESI-MS/MS定量分析及评价[J].中药材,2016,39(10):2264-2267,4.

基金项目

国家自然科学基金(81303233) (81303233)

中药材

OA北大核心CSTPCDMEDLINE

1001-4454

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