重庆医学2017，Vol.46Issue(12)：1613-1615,3.DOI:10.3969/j.issn.1671-8348.2017.12.009
血清CA125、HE4联合阴道彩色多普勒在卵巢癌高危人群早期筛查中的临床价值
Clinical value of serum CA125 and HE4 combined with vaginal color Doppler in early screening of ovarian cancer among high-risk populations
摘要
Abstract
Objective To explore the clinical value of serum CA125 and HE4 combined with transvaginal color Doppler(TVCD)examination in early screening of ovarian cancer among high-risk populations.Methods The included research subjects were divided into 3 groups:100 cases in the healthy group,80 cases in the high-risk group and 32 cases in the ovarian cancer group.The serum CA125 and HE4 levels and ultrasonic scores were compared among 3 groups.Results The HE4 and CA125 levels and ultrasound scores in the ovarian cancer group were significantly increased compared with the other two groups,the difference was statistically significant(P＜0.01);the positive detection rate of CA125 plus HE4 levels combined with ultrasonic examination in the high-risk group was higher than that of other detection method(P＜0.05);the sensitivity and specificity of CA125+HE4 combined with vaginal ultrasound screening were obviously higher than those of other screening method,the difference was statistically significant(P＜0.05);the specificity of HE4 was significantly higher than that of CA125,but its sensitivity was lower than that of CA125(P＜0.05).Conclusion CA125 and HE4 combined with TVCD is helpful for early screening of ovarian cancer in high-risk populations,easy to save medical cost and improves its detection rate.关键词
卵巢癌高危人群/CA125/HE4/阴道/超声检查,多普勒,彩色Key words
ovarian cancer risk groups/CA125/HE4/vagina/ultrasonography/Doppler/color分类
医药卫生引用本文复制引用
辜卫红,胡天惠,薛涛..血清CA125、HE4联合阴道彩色多普勒在卵巢癌高危人群早期筛查中的临床价值[J].重庆医学,2017,46(12):1613-1615,3.基金项目
江苏省淮安市科技计划项目--应用研究与科技攻关计划(社会发展)课题基金(HAS2014). （社会发展）
